About 4 results found for searched term "RIPK1-IN-10" (0.356 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M21565 | RIPK1-IN-10 | RIPK |
| Ripk1-in-10 is a potent inhibitor of RIPK1. | ||
| M5209 | GSK481 | RIPK |
| GSK481 is a highly effective, selective and specific RIPK1 inhibitor with an IC50 value of 1.3 nM, which can inhibit the phosphorylation of Ser166 in wild-type human RIPK1 (IC50 value of 2.8 nM). The IC50 value of GSK481 against U937 cells was 10 nM. | ||
| M10602 | Necrostatin 2 racemate | RIPK |
| Nec-1s; Necrostatin 1S; 7-Cl-O-Nec-1 | ||
| Necrostatin-2 racemate (also known as 7-Cl-O-Nec-1 and Nec-1s) is a potent and specific receptor-interacting protein kinase 1 (RIPK1) inhibitor lacking the IDO-targeting effect, with >1000-fold more selective for RIPK1 than for any other kinase out of 485 human kinases. | ||
| M21566 | RIPK1-IN-4 | RIPK |
| RIPK1-IN-4 is a potent type II kinase receptor interacting protein 1 (RIP1) kinase inhibitor and binds to the inactive form of RIP1 in D1-out. For RIP1 and ADP-Glo kinases, IC50 was 16 nM and 10 nM, respectively. | ||
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